UNC13A

unc-13 homolog A

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30988157 IMR-90 Human YES

GO terms:

Biological Process:
positive regulation of neurotransmitter secretion [GO:0001956],
neurotransmitter secretion [GO:0007269],
neuromuscular junction development [GO:0007528],
synaptic vesicle docking [GO:0016081],
synaptic vesicle priming [GO:0016082],
synaptic vesicle maturation [GO:0016188],
positive regulation of synaptic plasticity [GO:0031915],
synaptic transmission, glutamatergic [GO:0035249],
intracellular signal transduction [GO:0035556],
regulation of short-term neuronal synaptic plasticity [GO:0048172],
beta-amyloid metabolic process [GO:0050435],
regulation of synaptic transmission, glutamatergic [GO:0051966],
innervation [GO:0060384],
dense core granule priming [GO:0061789],
neuronal dense core vesicle exocytosis [GO:0099011],
presynaptic dense core vesicle exocytosis [GO:0099525],
positive regulation of glutamate receptor signaling pathway [GO:1900451],
regulation of amyloid precursor protein catabolic process [GO:1902991],
positive regulation of dendrite extension [GO:1903861],
exocytosis [GO:0006887],
chemical synaptic transmission [GO:0007268],
regulation of synaptic vesicle priming [GO:0010807],
synaptic vesicle exocytosis [GO:0016079],
cell differentiation [GO:0030154],
long-term synaptic potentiation [GO:0060291],
dense core granule docking [GO:0061790],

Molecular Function:
calcium ion binding [GO:0005509],
calmodulin binding [GO:0005516],
phospholipid binding [GO:0005543],
syntaxin-1 binding [GO:0017075],
diacylglycerol binding [GO:0019992],
SNARE binding [GO:0000149],
protein binding [GO:0005515],
protein domain specific binding [GO:0019904],
syntaxin binding [GO:0019905],
spectrin binding [GO:0030507],
identical protein binding [GO:0042802],
macromolecular complex binding [GO:0044877],
metal ion binding [GO:0046872],
protein N-terminus binding [GO:0047485],

Cellular Component:
plasma membrane [GO:0005886],
synaptic vesicle membrane [GO:0030672],
neuromuscular junction [GO:0031594],
presynaptic membrane [GO:0042734],
neuron projection [GO:0043005],
terminal bouton [GO:0043195],
calyx of Held [GO:0044305],
presynaptic active zone [GO:0048786],
presynaptic active zone cytoplasmic component [GO:0098831],
glutamatergic synapse [GO:0098978],
cytoplasm [GO:0005737],
Golgi-associated vesicle [GO:0005798],
membrane [GO:0016020],
cell junction [GO:0030054],
axon [GO:0030424],
macromolecular complex [GO:0032991],
cell projection [GO:0042995],
synapse [GO:0045202],
excitatory synapse [GO:0060076],
synaptic membrane [GO:0097060],
presynapse [GO:0098793],