TRHDE

thyrotropin releasing hormone degrading enzyme

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
signal transduction [GO:0007165],
cell-cell signaling [GO:0007267],
peptide catabolic process [GO:0043171],

Molecular Function:
aminopeptidase activity [GO:0004177],
zinc ion binding [GO:0008270],
peptide binding [GO:0042277],
metalloaminopeptidase activity [GO:0070006],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
extracellular exosome [GO:0070062],
membrane [GO:0016020],
integral component of membrane [GO:0016021],