tumor protein p53 inducible nuclear protein 2

Link to human ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Li Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
autophagosome assembly [GO:0000045],
osteoblast differentiation [GO:0001649],
tissue homeostasis [GO:0001894],
ubiquitin-dependent protein catabolic process [GO:0006511],
positive regulation of autophagy [GO:0010508],
positive regulation of transcription, DNA-templated [GO:0045893],
negative regulation of cellular protein localization [GO:1903828],

Molecular Function:
protein binding [GO:0005515],
ubiquitin binding [GO:0043130],

Cellular Component:
nucleus [GO:0005634],
autophagosome [GO:0005776],
cytosol [GO:0005829],
PML body [GO:0016605],
cytoplasmic vesicle [GO:0031410],