ACOX1

acyl-CoA oxidase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
very long-chain fatty acid metabolic process [GO:0000038],
generation of precursor metabolites and energy [GO:0006091],
protein targeting to peroxisome [GO:0006625],
lipid metabolic process [GO:0006629],
prostaglandin metabolic process [GO:0006693],
spermatogenesis [GO:0007283],
regulation of lipid metabolic process [GO:0019216],
fatty acid oxidation [GO:0019395],
fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540],
alpha-linolenic acid metabolic process [GO:0036109],
lipid homeostasis [GO:0055088],
fatty acid metabolic process [GO:0006631],
fatty acid beta-oxidation [GO:0006635],
peroxisome fission [GO:0016559],
cholesterol homeostasis [GO:0042632],
oxidation-reduction process [GO:0055114],

Molecular Function:
acyl-CoA oxidase activity [GO:0003997],
fatty acid binding [GO:0005504],
palmitoyl-CoA oxidase activity [GO:0016401],
PDZ domain binding [GO:0030165],
protein N-terminus binding [GO:0047485],
flavin adenine dinucleotide binding [GO:0050660],
FAD binding [GO:0071949],
oxidoreductase activity [GO:0016491],
oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627],
protein homodimerization activity [GO:0042803],

Cellular Component:
peroxisome [GO:0005777],
peroxisomal membrane [GO:0005778],
peroxisomal matrix [GO:0005782],
cytosol [GO:0005829],
membrane [GO:0016020],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],