BRCA1

BRCA1 DNA repair associated

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

GO terms:

Biological Process:
double-strand break repair via homologous recombination [GO:0000724],
DNA double-strand break processing [GO:0000729],
DNA replication [GO:0006260],
postreplication repair [GO:0006301],
double-strand break repair [GO:0006302],
double-strand break repair via nonhomologous end joining [GO:0006303],
regulation of gene expression by genetic imprinting [GO:0006349],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
regulation of transcription from RNA polymerase III promoter [GO:0006359],
fatty acid biosynthetic process [GO:0006633],
apoptotic process [GO:0006915],
cellular response to DNA damage stimulus [GO:0006974],
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978],
chromosome segregation [GO:0007059],
centrosome cycle [GO:0007098],
intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630],
dosage compensation by inactivation of X chromosome [GO:0009048],
response to ionizing radiation [GO:0010212],
positive regulation of vascular endothelial growth factor production [GO:0010575],
positive regulation of gene expression [GO:0010628],
protein ubiquitination [GO:0016567],
protein deubiquitination [GO:0016579],
androgen receptor signaling pathway [GO:0030521],
positive regulation of protein ubiquitination [GO:0031398],
negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147],
positive regulation of histone acetylation [GO:0035066],
negative regulation of histone acetylation [GO:0035067],
regulation of cell proliferation [GO:0042127],
regulation of apoptotic process [GO:0042981],
chordate embryonic development [GO:0043009],
response to estrogen [GO:0043627],
regulation of DNA methylation [GO:0044030],
mitotic G2/M transition checkpoint [GO:0044818],
negative regulation of fatty acid biosynthetic process [GO:0045717],
positive regulation of DNA repair [GO:0045739],
positive regulation of angiogenesis [GO:0045766],
negative regulation of transcription, DNA-templated [GO:0045892],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
negative regulation of centriole replication [GO:0046600],
positive regulation of histone H3-K4 methylation [GO:0051571],
negative regulation of histone H3-K4 methylation [GO:0051572],
negative regulation of histone H3-K9 methylation [GO:0051573],
positive regulation of histone H3-K9 methylation [GO:0051574],
protein autoubiquitination [GO:0051865],
negative regulation of G0 to G1 transition [GO:0070317],
positive regulation of histone H4-K20 methylation [GO:0070512],
positive regulation of cell cycle arrest [GO:0071158],
cellular response to tumor necrosis factor [GO:0071356],
cellular response to indole-3-methanol [GO:0071681],
signal transduction involved in G2 DNA damage checkpoint [GO:0072425],
protein K6-linked ubiquitination [GO:0085020],
regulation of signal transduction by p53 class mediator [GO:1901796],
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042],
negative regulation of reactive oxygen species metabolic process [GO:2000378],
positive regulation of histone H3-K9 acetylation [GO:2000617],
positive regulation of histone H4-K16 acetylation [GO:2000620],
DNA repair [GO:0006281],
DNA recombination [GO:0006310],
lipid metabolic process [GO:0006629],
fatty acid metabolic process [GO:0006631],
cell cycle [GO:0007049],
positive regulation of protein import into nucleus [GO:0042307],
centrosome duplication [GO:0051298],

Molecular Function:
transcription regulatory region sequence-specific DNA binding [GO:0000976],
DNA binding [GO:0003677],
damaged DNA binding [GO:0003684],
transcription coactivator activity [GO:0003713],
RNA binding [GO:0003723],
ubiquitin-protein transferase activity [GO:0004842],
protein binding [GO:0005515],
zinc ion binding [GO:0008270],
tubulin binding [GO:0015631],
enzyme binding [GO:0019899],
ubiquitin protein ligase binding [GO:0031625],
identical protein binding [GO:0042802],
androgen receptor binding [GO:0050681],
RNA polymerase binding [GO:0070063],
chromatin binding [GO:0003682],
transferase activity [GO:0016740],
metal ion binding [GO:0046872],

Cellular Component:
ubiquitin ligase complex [GO:0000151],
lateral element [GO:0000800],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
chromosome [GO:0005694],
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
gamma-tubulin ring complex [GO:0008274],
nuclear body [GO:0016604],
BRCA1-BARD1 complex [GO:0031436],
macromolecular complex [GO:0032991],
BRCA1-A complex [GO:0070531],
ribonucleoprotein complex [GO:1990904],
condensed chromosome [GO:0000793],
condensed nuclear chromosome [GO:0000794],
mitochondrial matrix [GO:0005759],
centrosome [GO:0005813],