TKT

transketolase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
xylulose biosynthetic process [GO:0005999],
pentose-phosphate shunt [GO:0006098],
pentose-phosphate shunt, non-oxidative branch [GO:0009052],
regulation of growth [GO:0040008],
glyceraldehyde-3-phosphate biosynthetic process [GO:0046166],
ribose phosphate biosynthetic process [GO:0046390],

Molecular Function:
magnesium ion binding [GO:0000287],
transketolase activity [GO:0004802],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
thiamine pyrophosphate binding [GO:0030976],
protein homodimerization activity [GO:0042803],
catalytic activity [GO:0003824],
transferase activity [GO:0016740],
carbohydrate binding [GO:0030246],
metal ion binding [GO:0046872],
monosaccharide binding [GO:0048029],

Cellular Component:
nucleoplasm [GO:0005654],
peroxisome [GO:0005777],
endoplasmic reticulum membrane [GO:0005789],
cytosol [GO:0005829],
nuclear body [GO:0016604],
nuclear speck [GO:0016607],
vesicle [GO:0031982],
extracellular exosome [GO:0070062],
myelin sheath [GO:0043209],
intracellular membrane-bounded organelle [GO:0043231],