THG1L

tRNA-histidine guanylyltransferase 1 like

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA522 Skin, Lung Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
tRNA modification [GO:0006400],
tRNA processing [GO:0008033],
protein homotetramerization [GO:0051289],

Molecular Function:
tRNA binding [GO:0000049],
magnesium ion binding [GO:0000287],
protein binding [GO:0005515],
ATP binding [GO:0005524],
GTP binding [GO:0005525],
tRNA guanylyltransferase activity [GO:0008193],
nucleotidyltransferase activity [GO:0016779],
identical protein binding [GO:0042802],
nucleotide binding [GO:0000166],
transferase activity [GO:0016740],
metal ion binding [GO:0046872],

Cellular Component:
mitochondrion [GO:0005739],
cytosol [GO:0005829],
transferase complex [GO:1990234],
cytoplasm [GO:0005737],