THBS2

thrombospondin 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31183403 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES
31964978 Primary astrocytes derived from brain Mouse YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
cell adhesion [GO:0007155],
negative regulation of angiogenesis [GO:0016525],
positive regulation of synapse assembly [GO:0051965],

Molecular Function:
extracellular matrix structural constituent [GO:0005201],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
heparin binding [GO:0008201],

Cellular Component:
extracellular region [GO:0005576],
basement membrane [GO:0005604],
platelet alpha granule [GO:0031091],
extracellular matrix [GO:0031012],