THBD

thrombomodulin

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Li Fraumeni Human YES
30988157 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES
32029712 Primary synovial fibroblast Human YES

GO terms:

Biological Process:
female pregnancy [GO:0007565],
blood coagulation [GO:0007596],
response to X-ray [GO:0010165],
negative regulation of platelet activation [GO:0010544],
negative regulation of blood coagulation [GO:0030195],
response to lipopolysaccharide [GO:0032496],
leukocyte migration [GO:0050900],
response to cAMP [GO:0051591],
negative regulation of fibrinolysis [GO:0051918],
hemostasis [GO:0007599],
embryo development [GO:0009790],
negative regulation of coagulation [GO:0050819],

Molecular Function:
transmembrane signaling receptor activity [GO:0004888],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
signaling receptor activity [GO:0038023],

Cellular Component:
extracellular space [GO:0005615],
vacuolar membrane [GO:0005774],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
external side of plasma membrane [GO:0009897],
cell surface [GO:0009986],
apicolateral plasma membrane [GO:0016327],
membrane [GO:0016020],
integral component of membrane [GO:0016021],