Link to human ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31878008 Heart Human NO

GO terms:

Biological Process:
retina homeostasis [GO:0001895],
platelet degranulation [GO:0002576],
cellular iron ion homeostasis [GO:0006879],
actin filament organization [GO:0007015],
activation of JUN kinase activity [GO:0007257],
response to bacterium [GO:0009617],
osteoclast differentiation [GO:0030316],
regulation of protein stability [GO:0031647],
transferrin transport [GO:0033572],
regulation of iron ion transport [GO:0034756],
post-translational protein modification [GO:0043687],
cellular protein metabolic process [GO:0044267],
positive regulation of bone resorption [GO:0045780],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of receptor-mediated endocytosis [GO:0048260],
iron ion homeostasis [GO:0055072],
SMAD protein signal transduction [GO:0060395],
membrane organization [GO:0061024],
ERK1 and ERK2 cascade [GO:0070371],
cellular response to iron ion [GO:0071281],
positive regulation of cell motility [GO:2000147],

Molecular Function:
protein binding [GO:0005515],
ferrous iron binding [GO:0008198],
ferric iron binding [GO:0008199],
iron chaperone activity [GO:0034986],
transferrin receptor binding [GO:1990459],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
early endosome [GO:0005769],
late endosome [GO:0005770],
endoplasmic reticulum lumen [GO:0005788],
clathrin-coated pit [GO:0005905],
basal plasma membrane [GO:0009925],
cell surface [GO:0009986],
endosome membrane [GO:0010008],
apical plasma membrane [GO:0016324],
endocytic vesicle [GO:0030139],
clathrin-coated vesicle membrane [GO:0030665],
extrinsic component of external side of plasma membrane [GO:0031232],
cytoplasmic vesicle [GO:0031410],
vesicle [GO:0031982],
secretory granule lumen [GO:0034774],
basal part of cell [GO:0045178],
perinuclear region of cytoplasm [GO:0048471],
recycling endosome [GO:0055037],
extracellular exosome [GO:0070062],
blood microparticle [GO:0072562],
HFE-transferrin receptor complex [GO:1990712],