ACOT8
acyl-CoA thioesterase 8
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
31945125 | Primary astrocytes derived from brain | Human | YES |
GO terms:
Biological Process:
protein targeting to peroxisome [GO:0006625],
acyl-CoA metabolic process [GO:0006637],
bile acid biosynthetic process [GO:0006699],
fatty acid catabolic process [GO:0009062],
viral process [GO:0016032],
peroxisome fission [GO:0016559],
fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540],
alpha-linolenic acid metabolic process [GO:0036109],
dicarboxylic acid catabolic process [GO:0043649],
negative regulation of CD4 biosynthetic process [GO:0045225],
lipid metabolic process [GO:0006629],
fatty acid metabolic process [GO:0006631],
peroxisome organization [GO:0007031],
Molecular Function:
acetyl-CoA hydrolase activity [GO:0003986],
succinyl-CoA hydrolase activity [GO:0004778],
protein binding [GO:0005515],
CoA hydrolase activity [GO:0016289],
palmitoyl-CoA hydrolase activity [GO:0016290],
choloyl-CoA hydrolase activity [GO:0033882],
acetoacetyl-CoA hydrolase activity [GO:0047603],
acyl-CoA hydrolase activity [GO:0047617],
hydroxymethylglutaryl-CoA hydrolase activity [GO:0047994],
carboxylic ester hydrolase activity [GO:0052689],
medium-chain acyl-CoA hydrolase activity [GO:0052815],
long-chain acyl-CoA hydrolase activity [GO:0052816],
hydrolase activity [GO:0016787],
Cellular Component:
peroxisomal matrix [GO:0005782],
cytosol [GO:0005829],
mitochondrion [GO:0005739],
peroxisome [GO:0005777],