TEAD4

TEA domain transcription factor 4

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
skeletal system development [GO:0001501],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
transcription initiation from RNA polymerase II promoter [GO:0006367],
muscle organ development [GO:0007517],
hippo signaling [GO:0035329],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
embryonic organ development [GO:0048568],
in utero embryonic development [GO:0001701],
cell fate specification [GO:0001708],
blastocyst formation [GO:0001825],
trophectodermal cell fate commitment [GO:0001830],
transcription, DNA-templated [GO:0006351],
regulation of transcription, DNA-templated [GO:0006355],
embryo implantation [GO:0007566],
cell fate commitment [GO:0045165],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of stem cell population maintenance [GO:1902459],

Molecular Function:
RNA polymerase II core promoter proximal region sequence-specific DNA binding [GO:0000978],
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding [GO:0001228],
transcription factor activity, sequence-specific DNA binding [GO:0003700],
protein binding [GO:0005515],
DNA binding [GO:0003677],
sequence-specific DNA binding [GO:0043565],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
transcription factor complex [GO:0005667],
cytoplasm [GO:0005737],
protein-DNA complex [GO:0032993],