TEAD1

TEA domain transcription factor 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31935369 PC-9, HCC827, HCC4007 Human NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES

GO terms:

Biological Process:
transcription initiation from RNA polymerase II promoter [GO:0006367],
hippo signaling [GO:0035329],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
embryonic organ development [GO:0048568],
macromolecular complex assembly [GO:0065003],
positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895],
embryonic heart tube morphogenesis [GO:0003143],
regulation of transcription, DNA-templated [GO:0006355],
heart development [GO:0007507],
regulation of gene expression [GO:0010468],
transition between fast and slow fiber [GO:0014883],
notochord development [GO:0030903],
regulation of cell proliferation [GO:0042127],
paraxial mesoderm development [GO:0048339],
lateral mesoderm development [GO:0048368],
cellular response to retinoic acid [GO:0071300],
positive regulation of protein serine/threonine kinase activity [GO:0071902],
positive regulation of stem cell population maintenance [GO:1902459],

Molecular Function:
RNA polymerase II core promoter proximal region sequence-specific DNA binding [GO:0000978],
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
core promoter proximal region sequence-specific DNA binding [GO:0000987],
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding [GO:0001228],
DNA binding [GO:0003677],
transcription factor activity, sequence-specific DNA binding [GO:0003700],
protein binding [GO:0005515],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
transcription factor complex [GO:0005667],
TEAD-1-YAP complex [GO:0071148],