BMPR1A

bone morphogenetic protein receptor type 1A

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
in utero embryonic development [GO:0001701],
mesoderm formation [GO:0001707],
somitogenesis [GO:0001756],
Mullerian duct regression [GO:0001880],
positive regulation of mesenchymal cell proliferation [GO:0002053],
chondrocyte differentiation [GO:0002062],
outflow tract septum morphogenesis [GO:0003148],
outflow tract morphogenesis [GO:0003151],
cardiac conduction system development [GO:0003161],
mitral valve morphogenesis [GO:0003183],
tricuspid valve morphogenesis [GO:0003186],
endocardial cushion morphogenesis [GO:0003203],
cardiac right ventricle morphogenesis [GO:0003215],
ventricular trabecula myocardium morphogenesis [GO:0003222],
ventricular compact myocardium morphogenesis [GO:0003223],
endocardial cushion formation [GO:0003272],
protein phosphorylation [GO:0006468],
immune response [GO:0006955],
transforming growth factor beta receptor signaling pathway [GO:0007179],
ectoderm development [GO:0007398],
dorsal/ventral axis specification [GO:0009950],
dorsal/ventral pattern formation [GO:0009953],
regulation of cardiac muscle cell apoptotic process [GO:0010665],
positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862],
neural crest cell development [GO:0014032],
negative regulation of smooth muscle cell migration [GO:0014912],
stem cell population maintenance [GO:0019827],
pituitary gland development [GO:0021983],
neural plate mediolateral regionalization [GO:0021998],
lung development [GO:0030324],
positive regulation of bone mineralization [GO:0030501],
BMP signaling pathway [GO:0030509],
hindlimb morphogenesis [GO:0035137],
dorsal aorta morphogenesis [GO:0035912],
odontogenesis of dentin-containing tooth [GO:0042475],
embryonic digit morphogenesis [GO:0042733],
positive regulation of osteoblast differentiation [GO:0045669],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
paraxial mesoderm structural organization [GO:0048352],
lateral mesoderm development [GO:0048368],
regulation of lateral mesodermal cell fate specification [GO:0048378],
mesendoderm development [GO:0048382],
embryonic organ development [GO:0048568],
developmental growth [GO:0048589],
positive regulation of epithelial cell proliferation [GO:0050679],
negative regulation of neurogenesis [GO:0050768],
palate development [GO:0060021],
regulation of cardiac muscle cell proliferation [GO:0060043],
positive regulation of cardiac muscle cell proliferation [GO:0060045],
positive regulation of SMAD protein import into nucleus [GO:0060391],
heart formation [GO:0060914],
BMP signaling pathway involved in heart development [GO:0061312],
pharyngeal arch artery morphogenesis [GO:0061626],
cellular response to growth factor stimulus [GO:0071363],
cellular response to BMP stimulus [GO:0071773],
positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895],
positive regulation of cardiac ventricle development [GO:1904414],
positive regulation of vascular smooth muscle cell proliferation [GO:1904707],
fibrous ring of heart morphogenesis [GO:1905285],
regulation of neural crest cell differentiation [GO:1905292],
regulation of cellular senescence [GO:2000772],
regulation of endothelial cell proliferation [GO:0001936],
heart morphogenesis [GO:0003007],
transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178],
pattern specification process [GO:0007389],
nervous system development [GO:0007399],
endoderm development [GO:0007492],
heart development [GO:0007507],
anterior/posterior pattern specification [GO:0009952],
phosphorylation [GO:0016310],
cell differentiation [GO:0030154],
regulation of endothelial cell differentiation [GO:0045601],
positive regulation of transcription, DNA-templated [GO:0045893],
paraxial mesoderm development [GO:0048339],
embryonic morphogenesis [GO:0048598],
cartilage development [GO:0051216],
neural plate pattern specification [GO:0060896],
regulation of neural crest cell fate specification [GO:1905295],

Molecular Function:
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
protein serine/threonine kinase activity [GO:0004674],
transmembrane receptor protein serine/threonine kinase activity [GO:0004675],
transforming growth factor beta receptor activity, type I [GO:0005025],
protein binding [GO:0005515],
ATP binding [GO:0005524],
protein homodimerization activity [GO:0042803],
SMAD binding [GO:0046332],
metal ion binding [GO:0046872],
BMP receptor activity [GO:0098821],
nucleotide binding [GO:0000166],
protein kinase activity [GO:0004672],
kinase activity [GO:0016301],
transferase activity [GO:0016740],

Cellular Component:
plasma membrane [GO:0005886],
caveola [GO:0005901],
external side of plasma membrane [GO:0009897],
integral component of membrane [GO:0016021],
dendrite [GO:0030425],
neuronal cell body [GO:0043025],
receptor complex [GO:0043235],
HFE-transferrin receptor complex [GO:1990712],
cell surface [GO:0009986],
membrane [GO:0016020],