serine/threonine kinase 40

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
26583757 HEK293T, IMR-90, MRC-5 Kidney, Lung Human NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
respiratory system process [GO:0003016],
glycogen metabolic process [GO:0005977],
protein phosphorylation [GO:0006468],
regulation of gene expression [GO:0010468],
phosphorylation [GO:0016310],
lung development [GO:0030324],
multicellular organism growth [GO:0035264],
negative regulation of apoptotic process [GO:0043066],
regulation of MAPK cascade [GO:0043408],
lung alveolus development [GO:0048286],
lung morphogenesis [GO:0060425],

Molecular Function:
nucleotide binding [GO:0000166],
protein kinase activity [GO:0004672],
protein serine/threonine kinase activity [GO:0004674],
protein binding [GO:0005515],
ATP binding [GO:0005524],
kinase activity [GO:0016301],
transferase activity [GO:0016740],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
cytosol [GO:0005829],