bone morphogenetic protein 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
30987592 MCF7 Breast Human YES
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
skeletal system development [GO:0001501],
cartilage condensation [GO:0001502],
ossification [GO:0001503],
proteolysis [GO:0006508],
signal transduction [GO:0007165],
multicellular organism development [GO:0007275],
extracellular matrix disassembly [GO:0022617],
cell differentiation [GO:0030154],
high-density lipoprotein particle assembly [GO:0034380],
positive regulation of cartilage development [GO:0061036],
cartilage development [GO:0051216],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
cytokine activity [GO:0005125],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
growth factor activity [GO:0008083],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
zinc ion binding [GO:0008270],
identical protein binding [GO:0042802],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
Golgi apparatus [GO:0005794],
vesicle [GO:0031982],