sushi repeat containing protein X-linked

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30987592 MCF7 Breast Human YES
31615473 WI-38, IMR-90, HUVEC, HAEC Human YES
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Li Fraumeni Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
phagolysosome assembly [GO:0001845],
autophagy [GO:0006914],
cell adhesion [GO:0007155],
response to endoplasmic reticulum stress [GO:0034976],
negative regulation of cell proliferation involved in contact inhibition [GO:0060244],
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241],

Molecular Function:
extracellular matrix structural constituent [GO:0005201],
protein binding [GO:0005515],

Cellular Component:
autophagosome [GO:0005776],
endoplasmic reticulum [GO:0005783],
cell surface [GO:0009986],
membrane [GO:0016020],