ACOT1

acyl-CoA thioesterase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

GO terms:

Biological Process:
long-chain fatty acid metabolic process [GO:0001676],
lipid metabolic process [GO:0006629],
fatty acid metabolic process [GO:0006631],
acyl-CoA metabolic process [GO:0006637],
negative regulation of cardiac muscle cell apoptotic process [GO:0010667],
very long-chain fatty acid metabolic process [GO:0000038],

Molecular Function:
palmitoyl-CoA hydrolase activity [GO:0016290],
hydrolase activity [GO:0016787],
thiolester hydrolase activity [GO:0016790],
acyl-CoA hydrolase activity [GO:0047617],
carboxylic ester hydrolase activity [GO:0052689],

Cellular Component:
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
cytosol [GO:0005829],