SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
signal transduction [GO:0007165],
negative regulation of cell migration [GO:0030336],
positive regulation of GTPase activity [GO:0043547],
regulation of small GTPase mediated signal transduction [GO:0051056],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
Rac GTPase binding [GO:0048365],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],