SPTBN1

spectrin beta, non-erythrocytic 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
16650383 MEF Stomach  Mouse NO
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
MAPK cascade [GO:0000165],
mitotic cytokinesis [GO:0000281],
ER to Golgi vesicle-mediated transport [GO:0006888],
plasma membrane organization [GO:0007009],
cytoskeleton organization [GO:0007010],
common-partner SMAD protein phosphorylation [GO:0007182],
axon guidance [GO:0007411],
Golgi to plasma membrane protein transport [GO:0043001],
actin filament capping [GO:0051693],
regulation of SMAD protein import into nucleus [GO:0060390],
membrane assembly [GO:0071709],
protein localization to plasma membrane [GO:0072659],
positive regulation of interleukin-2 secretion [GO:1900042],
regulation of protein localization to plasma membrane [GO:1903076],
positive regulation of protein localization to plasma membrane [GO:1903078],

Molecular Function:
RNA binding [GO:0003723],
actin binding [GO:0003779],
structural constituent of cytoskeleton [GO:0005200],
protein binding [GO:0005515],
calmodulin binding [GO:0005516],
phospholipid binding [GO:0005543],
ankyrin binding [GO:0030506],
macromolecular complex binding [GO:0044877],
cadherin binding [GO:0045296],
GTPase binding [GO:0051020],

Cellular Component:
nucleolus [GO:0005730],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
spectrin [GO:0008091],
postsynaptic density [GO:0014069],
spectrin-associated cytoskeleton [GO:0014731],
axolemma [GO:0030673],
M band [GO:0031430],
cuticular plate [GO:0032437],
extracellular exosome [GO:0070062],
glutamatergic synapse [GO:0098978],
nucleus [GO:0005634],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
membrane [GO:0016020],
cortical cytoskeleton [GO:0030863],
macromolecular complex [GO:0032991],
postsynapse [GO:0098794],