superoxide dismutase 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
21678067 C85 Human NO
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
29548335 Saos-2 Human YES
30977188 MSC Human YES
31945125 Primary astrocytes derived from brain Human YES
32671444 MDA-MB-231 Breast Human NO
32671444 MDA-MB-231 Breast Mouse NO

GO terms:

Biological Process:
response to hypoxia [GO:0001666],
removal of superoxide radicals [GO:0019430],
cellular response to oxidative stress [GO:0034599],
response to copper ion [GO:0046688],
oxidation-reduction process [GO:0055114],
superoxide metabolic process [GO:0006801],

Molecular Function:
superoxide dismutase activity [GO:0004784],
copper ion binding [GO:0005507],
protein binding [GO:0005515],
heparin binding [GO:0008201],
antioxidant activity [GO:0016209],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
nucleus [GO:0005634],
Golgi lumen [GO:0005796],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],