sorting nexin 9

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
mitotic cytokinesis [GO:0000281],
intracellular protein transport [GO:0006886],
endocytosis [GO:0006897],
receptor-mediated endocytosis [GO:0006898],
endosomal transport [GO:0016197],
positive regulation of actin filament polymerization [GO:0030838],
cleavage furrow formation [GO:0036089],
positive regulation of GTPase activity [GO:0043547],
positive regulation of protein kinase activity [GO:0045860],
positive regulation of membrane protein ectodomain proteolysis [GO:0051044],
lipid tube assembly [GO:0060988],
membrane organization [GO:0061024],
macromolecular complex assembly [GO:0065003],
membrane tubulation [GO:0097320],
mitotic cell cycle [GO:0000278],
cell cycle [GO:0007049],
protein transport [GO:0015031],
cell division [GO:0051301],

Molecular Function:
protein binding [GO:0005515],
1-phosphatidylinositol binding [GO:0005545],
ubiquitin protein ligase binding [GO:0031625],
phosphatidylinositol binding [GO:0035091],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
cadherin binding [GO:0045296],
Arp2/3 complex binding [GO:0071933],
lipid binding [GO:0008289],

Cellular Component:
ruffle [GO:0001726],
cytoplasm [GO:0005737],
trans-Golgi network [GO:0005802],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
clathrin-coated vesicle [GO:0030136],
cytoplasmic vesicle membrane [GO:0030659],
extrinsic component of cytoplasmic side of plasma membrane [GO:0031234],
cytoplasmic vesicle [GO:0031410],
cuticular plate [GO:0032437],
extracellular exosome [GO:0070062],
Golgi apparatus [GO:0005794],
membrane [GO:0016020],
cell projection [GO:0042995],