sorting nexin 10

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
gastric acid secretion [GO:0001696],
endocytosis [GO:0006897],
endosome organization [GO:0007032],
protein transport [GO:0015031],
bone mineralization [GO:0030282],
osteoclast differentiation [GO:0030316],
tooth eruption [GO:0044691],
bone resorption [GO:0045453],
calcium ion homeostasis [GO:0055074],
cilium assembly [GO:0060271],
protein localization to cilium [GO:0061512],
protein localization to centrosome [GO:0071539],
ruffle assembly [GO:0097178],
cellular response to leukemia inhibitory factor [GO:1990830],
cell projection organization [GO:0030030],
bone mineralization involved in bone maturation [GO:0035630],
bone remodeling [GO:0046849],

Molecular Function:
protein binding [GO:0005515],
1-phosphatidylinositol binding [GO:0005545],
ATPase binding [GO:0051117],
lipid binding [GO:0008289],
phosphatidylinositol binding [GO:0035091],

Cellular Component:
nucleus [GO:0005634],
endoplasmic reticulum [GO:0005783],
centrosome [GO:0005813],
secretory granule [GO:0030141],
extrinsic component of endosome membrane [GO:0031313],
apical cytoplasm [GO:0090651],
cytoplasm [GO:0005737],
endosome [GO:0005768],
cytoskeleton [GO:0005856],
membrane [GO:0016020],