ACKR2

atypical chemokine receptor 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
endocytosis [GO:0006897],
chemotaxis [GO:0006935],
inflammatory response [GO:0006954],
immune response [GO:0006955],
G-protein coupled receptor signaling pathway [GO:0007186],
positive regulation of cytosolic calcium ion concentration [GO:0007204],
multicellular organism development [GO:0007275],
calcium-mediated signaling [GO:0019722],
cell chemotaxis [GO:0060326],
chemokine-mediated signaling pathway [GO:0070098],
signal transduction [GO:0007165],

Molecular Function:
chemokine receptor activity [GO:0004950],
scavenger receptor activity [GO:0005044],
C-C chemokine receptor activity [GO:0016493],
chemokine binding [GO:0019956],
C-C chemokine binding [GO:0019957],
G-protein coupled receptor activity [GO:0004930],
protein binding [GO:0005515],

Cellular Component:
nucleoplasm [GO:0005654],
early endosome [GO:0005769],
cytosol [GO:0005829],
actin filament [GO:0005884],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
external side of plasma membrane [GO:0009897],
nuclear membrane [GO:0031965],
intracellular membrane-bounded organelle [GO:0043231],
recycling endosome [GO:0055037],
endosome [GO:0005768],
membrane [GO:0016020],
integral component of membrane [GO:0016021],