BGN

biglycan

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
blood vessel remodeling [GO:0001974],
biological_process [GO:0008150],
peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800],
extracellular matrix organization [GO:0030198],
chondroitin sulfate biosynthetic process [GO:0030206],
chondroitin sulfate catabolic process [GO:0030207],
dermatan sulfate biosynthetic process [GO:0030208],
bone development [GO:0060348],

Molecular Function:
extracellular matrix structural constituent [GO:0005201],
protein binding [GO:0005515],
glycosaminoglycan binding [GO:0005539],
extracellular matrix structural constituent conferring compression resistance [GO:0030021],
extracellular matrix binding [GO:0050840],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
Golgi lumen [GO:0005796],
cell surface [GO:0009986],
transport vesicle [GO:0030133],
extracellular matrix [GO:0031012],
sarcolemma [GO:0042383],
lysosomal lumen [GO:0043202],
extracellular exosome [GO:0070062],
intracellular [GO:0005622],