SIPA1L1

signal induced proliferation associated 1 like 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
biological_process [GO:0008150],
actin cytoskeleton reorganization [GO:0031532],
regulation of GTPase activity [GO:0043087],
ephrin receptor signaling pathway [GO:0048013],
regulation of synaptic plasticity [GO:0048167],
regulation of axonogenesis [GO:0050770],
regulation of small GTPase mediated signal transduction [GO:0051056],
regulation of dendritic spine morphogenesis [GO:0061001],
activation of GTPase activity [GO:0090630],
regulation of dendrite morphogenesis [GO:0048814],
postsynaptic actin cytoskeleton organization [GO:0098974],

Molecular Function:
molecular_function [GO:0003674],
GTPase activator activity [GO:0005096],
ephrin receptor binding [GO:0046875],
protein kinase binding [GO:0019901],
ubiquitin protein ligase binding [GO:0031625],
macromolecular complex binding [GO:0044877],
actin filament binding [GO:0051015],

Cellular Component:
cellular_component [GO:0005575],
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],
postsynaptic density [GO:0014069],
dendritic spine [GO:0043197],
cell junction [GO:0030054],
macromolecular complex [GO:0032991],
neuron projection [GO:0043005],
neuronal cell body [GO:0043025],
synapse [GO:0045202],
postsynapse [GO:0098794],
glutamatergic synapse [GO:0098978],