SHC3

SHC adaptor protein 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
signal transduction [GO:0007165],
transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169],
central nervous system development [GO:0007417],
learning or memory [GO:0007611],
synaptic transmission, glutamatergic [GO:0035249],
intracellular signal transduction [GO:0035556],
MAPK cascade [GO:0000165],
epidermal growth factor receptor signaling pathway [GO:0007173],
Ras protein signal transduction [GO:0007265],
axon guidance [GO:0007411],

Molecular Function:
phosphotyrosine binding [GO:0001784],
protein binding [GO:0005515],
receptor tyrosine kinase binding [GO:0030971],

Cellular Component:
plasma membrane [GO:0005886],
cellular_component [GO:0005575],
cytosol [GO:0005829],
synapse [GO:0045202],