SH3 domain containing GRB2 like, endophilin B1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
autophagy [GO:0006914],
apoptotic process [GO:0006915],
positive regulation of autophagy [GO:0010508],
regulation of macroautophagy [GO:0016241],
positive regulation of protein complex assembly [GO:0031334],
regulation of protein stability [GO:0031647],
regulation of cytokinesis [GO:0032465],
receptor catabolic process [GO:0032801],
cellular response to amino acid starvation [GO:0034198],
cellular response to glucose starvation [GO:0042149],
autophagic cell death [GO:0048102],
membrane fission [GO:0090148],
positive regulation of membrane tubulation [GO:1903527],
protein localization to vacuolar membrane [GO:1903778],
positive regulation of protein targeting to mitochondrion [GO:1903955],
positive regulation of autophagosome assembly [GO:2000786],
phosphatidic acid biosynthetic process [GO:0006654],
mitochondrion organization [GO:0007005],
phospholipid biosynthetic process [GO:0008654],
positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552],
positive regulation of dendrite morphogenesis [GO:0050775],
'de novo' posttranslational protein folding [GO:0051084],
positive regulation of neurotrophin TRK receptor signaling pathway [GO:0051388],
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740],
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254],
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255],
positive regulation of dendrite extension [GO:1903861],
regulation of early endosome to late endosome transport [GO:2000641],

Molecular Function:
protein binding [GO:0005515],
lipid binding [GO:0008289],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
cadherin binding [GO:0045296],
fatty acid binding [GO:0005504],
lysophosphatidic acid acyltransferase activity [GO:0042171],

Cellular Component:
Golgi membrane [GO:0000139],
autophagosome membrane [GO:0000421],
cytoplasm [GO:0005737],
mitochondrial outer membrane [GO:0005741],
cytosol [GO:0005829],
midbody [GO:0030496],
cytoplasmic vesicle [GO:0031410],
macromolecular complex [GO:0032991],
mitochondrion [GO:0005739],
mitochondrial envelope [GO:0005740],
early endosome [GO:0005769],
endoplasmic reticulum [GO:0005783],
Golgi apparatus [GO:0005794],
synaptic vesicle [GO:0008021],
membrane [GO:0016020],
neuron projection [GO:0043005],
neuronal cell body [GO:0043025],