SEMA3A

semaphorin 3A

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
neural crest cell migration [GO:0001755],
neuron migration [GO:0001764],
regulation of heart rate [GO:0002027],
apoptotic process [GO:0006915],
axon guidance [GO:0007411],
axonal fasciculation [GO:0007413],
motor neuron axon guidance [GO:0008045],
negative regulation of epithelial cell migration [GO:0010633],
negative regulation of neuron projection development [GO:0010977],
facial nerve structural organization [GO:0021612],
trigeminal nerve structural organization [GO:0021637],
nerve development [GO:0021675],
olfactory bulb development [GO:0021772],
branchiomotor neuron axon guidance [GO:0021785],
gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828],
positive regulation of cell migration [GO:0030335],
ventral trunk neural crest cell migration [GO:0036486],
positive regulation of JNK cascade [GO:0046330],
sympathetic nervous system development [GO:0048485],
regulation of axon extension involved in axon guidance [GO:0048841],
negative regulation of axon extension involved in axon guidance [GO:0048843],
axon extension involved in axon guidance [GO:0048846],
sensory system development [GO:0048880],
negative chemotaxis [GO:0050919],
axonogenesis involved in innervation [GO:0060385],
dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666],
sympathetic ganglion development [GO:0061549],
trigeminal ganglion development [GO:0061551],
semaphorin-plexin signaling pathway [GO:0071526],
sympathetic neuron projection extension [GO:0097490],
sympathetic neuron projection guidance [GO:0097491],
neural crest cell migration involved in autonomic nervous system development [GO:1901166],
semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285],
semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287],
neural crest cell migration involved in sympathetic nervous system development [GO:1903045],
facioacoustic ganglion development [GO:1903375],
positive regulation of male gonad development [GO:2000020],
positive regulation of neuron migration [GO:2001224],
multicellular organism development [GO:0007275],
nervous system development [GO:0007399],
cell differentiation [GO:0030154],
negative regulation of axon extension [GO:0030517],
dendrite morphogenesis [GO:0048813],

Molecular Function:
semaphorin receptor binding [GO:0030215],
neuropilin binding [GO:0038191],
chemorepellent activity [GO:0045499],
protein binding [GO:0005515],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
integral component of plasma membrane [GO:0005887],
axon [GO:0030424],
dendrite [GO:0030425],