SCP2

sterol carrier protein 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30790400 Primary endothelial cells derived from lung Mouse NO

GO terms:

Biological Process:
protein targeting to peroxisome [GO:0006625],
fatty acid beta-oxidation [GO:0006635],
steroid biosynthetic process [GO:0006694],
bile acid biosynthetic process [GO:0006699],
bile acid metabolic process [GO:0008206],
phospholipid transport [GO:0015914],
positive regulation of intracellular cholesterol transport [GO:0032385],
fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540],
alpha-linolenic acid metabolic process [GO:0036109],
lipid hydroperoxide transport [GO:1901373],
acyl-CoA metabolic process [GO:0006637],
progesterone biosynthetic process [GO:0006701],
lipid transport [GO:0006869],
peroxisome organization [GO:0007031],
aging [GO:0007568],
positive regulation of steroid biosynthetic process [GO:0010893],
inositol trisphosphate biosynthetic process [GO:0032959],
positive regulation of apoptotic process [GO:0043065],
positive regulation of cholesterol biosynthetic process [GO:0045542],
positive regulation of steroid metabolic process [GO:0045940],
protein localization to plasma membrane [GO:0072659],
positive regulation of cholesterol import [GO:1904109],

Molecular Function:
fatty-acyl-CoA binding [GO:0000062],
acetyl-CoA C-acyltransferase activity [GO:0003988],
receptor binding [GO:0005102],
protein binding [GO:0005515],
cholesterol binding [GO:0015485],
sterol binding [GO:0032934],
propanoyl-CoA C-acyltransferase activity [GO:0033814],
long-chain fatty acyl-CoA binding [GO:0036042],
propionyl-CoA C2-trimethyltridecanoyltransferase activity [GO:0050632],
acetyl-CoA C-myristoyltransferase activity [GO:0050633],
oleic acid binding [GO:0070538],
catalytic activity [GO:0003824],
lipid binding [GO:0008289],
phosphatidylinositol transporter activity [GO:0008526],
transferase activity [GO:0016740],
transferase activity, transferring acyl groups [GO:0016746],
transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747],
identical protein binding [GO:0042802],
macromolecular complex binding [GO:0044877],
phosphatidylethanolamine transporter activity [GO:1904121],

Cellular Component:
nucleoplasm [GO:0005654],
mitochondrion [GO:0005739],
peroxisome [GO:0005777],
peroxisomal matrix [GO:0005782],
cytosol [GO:0005829],
membrane [GO:0016020],
macromolecular complex [GO:0032991],
intracellular membrane-bounded organelle [GO:0043231],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
endoplasmic reticulum [GO:0005783],
extrinsic component of membrane [GO:0019898],
extrinsic component of mitochondrial outer membrane [GO:0031315],