SCARB2

scavenger receptor class B member 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
protein targeting to lysosome [GO:0006622],
receptor-mediated endocytosis [GO:0006898],
positive regulation of neuron projection development [GO:0010976],
aminophospholipid transport [GO:0015917],
regulation of cellular carbohydrate catabolic process [GO:0043471],
viral entry into host cell [GO:0046718],
membrane organization [GO:0061024],
regulation of endosome organization [GO:1904978],
regulation of glucosylceramidase activity [GO:1905123],

Molecular Function:
virus receptor activity [GO:0001618],
phosphatidylserine binding [GO:0001786],
transmembrane signaling receptor activity [GO:0004888],
scavenger receptor activity [GO:0005044],
protein binding [GO:0005515],
cholesterol binding [GO:0015485],
enzyme binding [GO:0019899],
phosphatidylcholine binding [GO:0031210],
cargo receptor activity [GO:0038024],
protein homodimerization activity [GO:0042803],
chaperone binding [GO:0051087],

Cellular Component:
Golgi membrane [GO:0000139],
lysosomal membrane [GO:0005765],
endoplasmic reticulum membrane [GO:0005789],
plasma membrane [GO:0005886],
focal adhesion [GO:0005925],
endosome membrane [GO:0010008],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
clathrin-coated vesicle membrane [GO:0030665],
endocytic vesicle membrane [GO:0030666],
late endosome membrane [GO:0031902],
lysosomal lumen [GO:0043202],
extracellular exosome [GO:0070062],
lysosome [GO:0005764],