SCARB1

scavenger receptor class B member 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
29548335 Li Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
endothelial cell proliferation [GO:0001935],
androgen biosynthetic process [GO:0006702],
cholesterol catabolic process [GO:0006707],
receptor-mediated endocytosis [GO:0006898],
positive regulation of endothelial cell migration [GO:0010595],
positive regulation of triglyceride biosynthetic process [GO:0010867],
positive regulation of cholesterol storage [GO:0010886],
regulation of phosphatidylcholine catabolic process [GO:0010899],
phospholipid transport [GO:0015914],
lipopolysaccharide transport [GO:0015920],
lipopolysaccharide-mediated signaling pathway [GO:0031663],
detection of lipopolysaccharide [GO:0032497],
cholesterol efflux [GO:0033344],
high-density lipoprotein particle remodeling [GO:0034375],
low-density lipoprotein particle clearance [GO:0034383],
high-density lipoprotein particle clearance [GO:0034384],
vitamin transmembrane transport [GO:0035461],
wound healing [GO:0042060],
cholesterol homeostasis [GO:0042632],
blood vessel endothelial cell migration [GO:0043534],
recognition of apoptotic cell [GO:0043654],
reverse cholesterol transport [GO:0043691],
adhesion of symbiont to host [GO:0044406],
viral entry into host cell [GO:0046718],
regulation of phagocytosis [GO:0050764],
intestinal absorption [GO:0050892],
positive regulation of nitric-oxide synthase activity [GO:0051000],
triglyceride homeostasis [GO:0070328],
cholesterol import [GO:0070508],
lipid transport [GO:0006869],
phagocytosis, recognition [GO:0006910],
cholesterol transport [GO:0030301],

Molecular Function:
lipopolysaccharide binding [GO:0001530],
beta-amyloid binding [GO:0001540],
virus receptor activity [GO:0001618],
phosphatidylserine binding [GO:0001786],
lipopolysaccharide receptor activity [GO:0001875],
scavenger receptor activity [GO:0005044],
transporter activity [GO:0005215],
protein binding [GO:0005515],
1-phosphatidylinositol binding [GO:0005545],
high-density lipoprotein particle binding [GO:0008035],
low-density lipoprotein particle binding [GO:0030169],
apolipoprotein binding [GO:0034185],
apolipoprotein A-I binding [GO:0034186],
identical protein binding [GO:0042802],
high-density lipoprotein particle receptor activity [GO:0070506],

Cellular Component:
lysosomal membrane [GO:0005765],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
caveola [GO:0005901],
cell surface [GO:0009986],
endocytic vesicle membrane [GO:0030666],
microvillus membrane [GO:0031528],
intracellular membrane-bounded organelle [GO:0043231],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],
membrane [GO:0016020],
integral component of membrane [GO:0016021],