BAR/IMD domain containing adaptor protein 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31534052 Kidney Mouse NO

GO terms:

Biological Process:
plasma membrane organization [GO:0007009],
axonogenesis [GO:0007409],
brain development [GO:0007420],
insulin receptor signaling pathway [GO:0008286],
regulation of cell shape [GO:0008360],
response to bacterium [GO:0009617],
dendrite development [GO:0016358],
positive regulation of actin filament polymerization [GO:0030838],
regulation of actin cytoskeleton organization [GO:0032956],
protein localization to synapse [GO:0035418],
Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096],
vascular endothelial growth factor receptor signaling pathway [GO:0048010],
regulation of synaptic plasticity [GO:0048167],
actin filament bundle assembly [GO:0051017],
actin crosslink formation [GO:0051764],
positive regulation of dendritic spine morphogenesis [GO:0061003],
cellular response to epidermal growth factor stimulus [GO:0071364],
cell-cell adhesion [GO:0098609],
modification of synaptic structure, modulating synaptic transmission [GO:0099564],
cellular response to L-glutamate [GO:1905232],
regulation of modification of postsynaptic actin cytoskeleton [GO:1905274],
positive regulation of actin cytoskeleton reorganization [GO:2000251],
positive regulation of excitatory postsynaptic potential [GO:2000463],
Rho protein signal transduction [GO:0007266],
positive regulation of neuron projection development [GO:0010976],
modulation of synaptic transmission [GO:0050804],

Molecular Function:
transcription cofactor binding [GO:0001221],
protein binding [GO:0005515],
protein C-terminus binding [GO:0008022],
cytoskeletal adaptor activity [GO:0008093],
PDZ domain binding [GO:0030165],
identical protein binding [GO:0042802],
proline-rich region binding [GO:0070064],
scaffold protein binding [GO:0097110],
cadherin binding involved in cell-cell adhesion [GO:0098641],

Cellular Component:
ruffle [GO:0001726],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
rough endoplasmic reticulum [GO:0005791],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
microtubule [GO:0005874],
plasma membrane [GO:0005886],
adherens junction [GO:0005912],
actin cytoskeleton [GO:0015629],
secretory granule [GO:0030141],
filopodium [GO:0030175],
neuronal cell body [GO:0043025],
dendritic shaft [GO:0043198],
neuron projection terminus [GO:0044306],
excitatory synapse [GO:0060076],
extracellular exosome [GO:0070062],
synaptic membrane [GO:0097060],
glutamatergic synapse [GO:0098978],
presynaptic cytosol [GO:0099523],
postsynaptic cytosol [GO:0099524],
cytoskeleton [GO:0005856],
postsynaptic density [GO:0014069],
membrane [GO:0016020],
cell projection [GO:0042995],
neuron projection [GO:0043005],
dendritic spine [GO:0043197],
presynapse [GO:0098793],
postsynapse [GO:0098794],