raftlin, lipid raft linker 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30987592 MCF7 Breast Human YES
31155234 heart heart Human NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Li Fraumeni Human YES
31983656 MSC Human YES
33296652 heart heart Human NO

GO terms:

Biological Process:
membrane raft assembly [GO:0001765],
T cell antigen processing and presentation [GO:0002457],
protein transport into membrane raft [GO:0032596],
interleukin-17 production [GO:0032620],
dsRNA transport [GO:0033227],
toll-like receptor 3 signaling pathway [GO:0034138],
positive regulation of growth rate [GO:0040010],
response to exogenous dsRNA [GO:0043330],
T cell receptor signaling pathway [GO:0050852],
B cell receptor signaling pathway [GO:0050853],
protein localization to membrane raft [GO:1903044],

Molecular Function:
double-stranded RNA binding [GO:0003725],

Cellular Component:
cytoplasm [GO:0005737],
endosome [GO:0005768],
early endosome [GO:0005769],
plasma membrane [GO:0005886],
macromolecular complex [GO:0032991],
membrane raft [GO:0045121],
extracellular exosome [GO:0070062],
membrane [GO:0016020],