RFTN1
raftlin, lipid raft linker 1
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 30987592 | MCF7 | Breast | Human | YES |
| 31155234 | heart | heart | Human | NO |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 29548335 | Li Fraumeni | Human | YES | |
| 31983656 | MSC | Human | YES | |
| 33296652 | heart | heart | Human | NO |
GO terms:
Biological Process:
membrane raft assembly [GO:0001765],
T cell antigen processing and presentation [GO:0002457],
protein transport into membrane raft [GO:0032596],
interleukin-17 production [GO:0032620],
dsRNA transport [GO:0033227],
toll-like receptor 3 signaling pathway [GO:0034138],
positive regulation of growth rate [GO:0040010],
response to exogenous dsRNA [GO:0043330],
T cell receptor signaling pathway [GO:0050852],
B cell receptor signaling pathway [GO:0050853],
protein localization to membrane raft [GO:1903044],
Molecular Function:
double-stranded RNA binding [GO:0003725],
Cellular Component:
cytoplasm [GO:0005737],
endosome [GO:0005768],
early endosome [GO:0005769],
plasma membrane [GO:0005886],
macromolecular complex [GO:0032991],
membrane raft [GO:0045121],
extracellular exosome [GO:0070062],
membrane [GO:0016020],