REV1 DNA directed polymerase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
DNA replication [GO:0006260],
response to UV [GO:0009411],
translesion synthesis [GO:0019985],
error-prone translesion synthesis [GO:0042276],
error-free translesion synthesis [GO:0070987],
DNA repair [GO:0006281],
cellular response to DNA damage stimulus [GO:0006974],
DNA biosynthetic process [GO:0071897],

Molecular Function:
damaged DNA binding [GO:0003684],
DNA-directed DNA polymerase activity [GO:0003887],
protein binding [GO:0005515],
deoxycytidyl transferase activity [GO:0017125],
metal ion binding [GO:0046872],
DNA binding [GO:0003677],
transferase activity [GO:0016740],
nucleotidyltransferase activity [GO:0016779],

Cellular Component:
nucleoplasm [GO:0005654],
nucleus [GO:0005634],