B4GALT7
beta-1,4-galactosyltransferase 7
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
28844647 | BJ, WI-38, IMR-90, MRC-5, HFF, HCA72 | Skin, Lung | Human | YES |
31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
29548335 | Saos-2 | Human | YES |
GO terms:
Biological Process:
carbohydrate metabolic process [GO:0005975],
glycosaminoglycan biosynthetic process [GO:0006024],
proteoglycan metabolic process [GO:0006029],
cellular protein modification process [GO:0006464],
protein N-linked glycosylation [GO:0006487],
glycosaminoglycan metabolic process [GO:0030203],
negative regulation of fibroblast proliferation [GO:0048147],
fibril organization [GO:0097435],
Molecular Function:
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831],
protein binding [GO:0005515],
galactosyltransferase activity [GO:0008378],
manganese ion binding [GO:0030145],
xylosylprotein 4-beta-galactosyltransferase activity [GO:0046525],
transferase activity [GO:0016740],
transferase activity, transferring glycosyl groups [GO:0016757],
metal ion binding [GO:0046872],
Cellular Component:
Golgi membrane [GO:0000139],
Golgi apparatus [GO:0005794],
integral component of membrane [GO:0016021],
Golgi cisterna membrane [GO:0032580],
membrane [GO:0016020],