RACK1

receptor for activated C kinase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29048616 Ca Ski Cervus Human NO

GO terms:

Biological Process:
positive regulation of protein phosphorylation [GO:0001934],
apoptotic process [GO:0006915],
activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919],
cell cycle [GO:0007049],
gastrulation [GO:0007369],
negative regulation of gene expression [GO:0010629],
regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803],
viral process [GO:0016032],
protein ubiquitination [GO:0016567],
negative regulation of translation [GO:0017148],
negative regulation of Wnt signaling pathway [GO:0030178],
negative regulation of cell growth [GO:0030308],
positive regulation of cell migration [GO:0030335],
positive regulation of protein complex assembly [GO:0031334],
negative regulation of protein binding [GO:0032091],
positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436],
regulation of protein localization [GO:0032880],
negative regulation of peptidyl-serine phosphorylation [GO:0033137],
positive regulation of Golgi to plasma membrane protein transport [GO:0042998],
positive regulation of apoptotic process [GO:0043065],
pigmentation [GO:0043473],
positive regulation of GTPase activity [GO:0043547],
rhythmic process [GO:0048511],
negative regulation of phagocytosis [GO:0050765],
regulation of cell division [GO:0051302],
positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343],
regulation of cell cycle [GO:0051726],
negative regulation of protein kinase B signaling [GO:0051898],
positive regulation of mitochondrial depolarization [GO:0051901],
negative regulation of protein tyrosine kinase activity [GO:0061099],
cellular response to glucose stimulus [GO:0071333],
cellular response to growth factor stimulus [GO:0071363],
rescue of stalled ribosome [GO:0072344],
negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102],
negative regulation of hydrogen peroxide-induced neuron death [GO:1903208],
regulation of establishment of cell polarity [GO:2000114],
positive regulation of ceramide biosynthetic process [GO:2000304],
positive regulation of gastrulation [GO:2000543],
positive regulation of intrinsic apoptotic signaling pathway [GO:2001244],
translation [GO:0006412],
regulation of translation [GO:0006417],
multicellular organism development [GO:0007275],
protein localization [GO:0008104],
intracellular signal transduction [GO:0035556],
regulation of growth [GO:0040008],
regulation of protein localization to plasma membrane [GO:1903076],

Molecular Function:
RNA binding [GO:0003723],
protein kinase C binding [GO:0005080],
receptor binding [GO:0005102],
protein binding [GO:0005515],
ion channel inhibitor activity [GO:0008200],
cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656],
enzyme binding [GO:0019899],
protein phosphatase binding [GO:0019903],
protein tyrosine kinase inhibitor activity [GO:0030292],
cyclin binding [GO:0030332],
receptor tyrosine kinase binding [GO:0030971],
signaling adaptor activity [GO:0035591],
SH2 domain binding [GO:0042169],
protein homodimerization activity [GO:0042803],
ribosome binding [GO:0043022],
cadherin binding [GO:0045296],
BH3 domain binding [GO:0051434],
binding, bridging [GO:0060090],
signaling receptor activity [GO:0038023],

Cellular Component:
phagocytic cup [GO:0001891],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
cytosol [GO:0005829],
small ribosomal subunit [GO:0015935],
cytosolic small ribosomal subunit [GO:0022627],
dendrite [GO:0030425],
midbody [GO:0030496],
neuronal cell body [GO:0043025],
perikaryon [GO:0043204],
intracellular membrane-bounded organelle [GO:0043231],
perinuclear region of cytoplasm [GO:0048471],
extracellular exosome [GO:0070062],
IRE1-RACK1-PP2A complex [GO:1990630],
ribosome [GO:0005840],
plasma membrane [GO:0005886],
membrane [GO:0016020],
cell projection [GO:0042995],
neuron projection [GO:0043005],
cell body [GO:0044297],