PTPN4

protein tyrosine phosphatase non-receptor type 4

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
protein dephosphorylation [GO:0006470],
peptidyl-tyrosine dephosphorylation [GO:0035335],
cellular response to cytokine stimulus [GO:0071345],
dephosphorylation [GO:0016311],

Molecular Function:
protein tyrosine phosphatase activity [GO:0004725],
non-membrane spanning protein tyrosine phosphatase activity [GO:0004726],
protein binding [GO:0005515],
cytoskeletal protein binding [GO:0008092],
phosphoprotein phosphatase activity [GO:0004721],
hydrolase activity [GO:0016787],
phosphatase activity [GO:0016791],

Cellular Component:
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
cytoplasmic side of plasma membrane [GO:0009898],
plasma membrane [GO:0005886],
membrane [GO:0016020],