ACAT2
acetyl-CoA acetyltransferase 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945054 | IMR-90 | Human | YES | |
| 31983656 | MSC | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
| 31983656 | IPSC-MSC | Human | YES | |
GO terms:
Biological Process:
lipid metabolic process [GO:0006629],
fatty acid beta-oxidation [GO:0006635],
cholesterol biosynthetic process [GO:0006695],
positive regulation of intestinal cholesterol absorption [GO:0045797],
Molecular Function:
acetyl-CoA C-acetyltransferase activity [GO:0003985],
acetyl-CoA C-acyltransferase activity [GO:0003988],
protein binding [GO:0005515],
catalytic activity [GO:0003824],
transferase activity [GO:0016740],
transferase activity, transferring acyl groups [GO:0016746],
transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747],
Cellular Component:
nucleoplasm [GO:0005654],
nucleolus [GO:0005730],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
cytosol [GO:0005829],
extracellular exosome [GO:0070062],