PSPH

phosphoserine phosphatase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
in utero embryonic development [GO:0001701],
L-serine metabolic process [GO:0006563],
L-serine biosynthetic process [GO:0006564],
response to mechanical stimulus [GO:0009612],
dephosphorylation [GO:0016311],
response to nutrient levels [GO:0031667],
response to testosterone [GO:0033574],
cellular amino acid biosynthetic process [GO:0008652],

Molecular Function:
magnesium ion binding [GO:0000287],
phosphoserine phosphatase activity [GO:0004647],
calcium ion binding [GO:0005509],
phosphatase activity [GO:0016791],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
neuron projection [GO:0043005],