ACAT1

acetyl-CoA acetyltransferase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
liver development [GO:0001889],
acetyl-CoA biosynthetic process [GO:0006085],
isoleucine catabolic process [GO:0006550],
fatty acid beta-oxidation [GO:0006635],
brain development [GO:0007420],
branched-chain amino acid catabolic process [GO:0009083],
response to hormone [GO:0009725],
response to organic cyclic compound [GO:0014070],
coenzyme A metabolic process [GO:0015936],
coenzyme A biosynthetic process [GO:0015937],
cholesterol esterification [GO:0034435],
response to starvation [GO:0042594],
acetyl-CoA catabolic process [GO:0046356],
ketone body biosynthetic process [GO:0046951],
ketone body catabolic process [GO:0046952],
adipose tissue development [GO:0060612],
metanephric proximal convoluted tubule development [GO:0072229],
ketone body metabolic process [GO:1902224],
propionyl-CoA biosynthetic process [GO:1902860],
lipid metabolic process [GO:0006629],
fatty acid metabolic process [GO:0006631],

Molecular Function:
acetyl-CoA C-acetyltransferase activity [GO:0003985],
acetyl-CoA C-acyltransferase activity [GO:0003988],
C-acetyltransferase activity [GO:0016453],
enzyme binding [GO:0019899],
potassium ion binding [GO:0030955],
identical protein binding [GO:0042802],
catalytic activity [GO:0003824],
transferase activity [GO:0016740],
transferase activity, transferring acyl groups [GO:0016746],
transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747],
metal ion binding [GO:0046872],

Cellular Component:
mitochondrion [GO:0005739],
mitochondrial matrix [GO:0005759],
extracellular exosome [GO:0070062],
mitochondrial inner membrane [GO:0005743],