phosphoribosyl transferase domain containing 1

Link to human ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
purine ribonucleoside salvage [GO:0006166],
guanine salvage [GO:0006178],
GMP catabolic process [GO:0046038],

Molecular Function:
nucleotide binding [GO:0000166],
magnesium ion binding [GO:0000287],
hypoxanthine phosphoribosyltransferase activity [GO:0004422],
protein binding [GO:0005515],
protein homodimerization activity [GO:0042803],