AVEN

apoptosis and caspase activation inhibitor

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
apoptotic process [GO:0006915],
negative regulation of G2/M transition of mitotic cell cycle [GO:0010972],
negative regulation of apoptotic process [GO:0043066],

Molecular Function:
protein binding [GO:0005515],
molecular_function [GO:0003674],

Cellular Component:
cytosol [GO:0005829],
endomembrane system [GO:0012505],
membrane [GO:0016020],