activator of transcription and developmental regulator AUTS2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA651 Skin, Lung Human YES
30988157 IMR-90 Human YES
33296652 heart heart Human NO

GO terms:

Biological Process:
neuron migration [GO:0001764],
positive regulation of lamellipodium assembly [GO:0010592],
actin cytoskeleton reorganization [GO:0031532],
positive regulation of Rac protein signal transduction [GO:0035022],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
axon extension [GO:0048675],
positive regulation of histone H3-K4 methylation [GO:0051571],
dendrite extension [GO:0097484],
positive regulation of histone H4-K16 acetylation [GO:2000620],
righting reflex [GO:0060013],
innate vocalization behavior [GO:0098582],

Molecular Function:
chromatin binding [GO:0003682],
protein binding [GO:0005515],

Cellular Component:
cellular_component [GO:0005575],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
actin cytoskeleton [GO:0015629],
growth cone [GO:0030426],
cytoskeleton [GO:0005856],
cell projection [GO:0042995],