PRKCQ

protein kinase C theta

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
regulation of cell growth [GO:0001558],
regulation of transcription, DNA-templated [GO:0006355],
membrane protein ectodomain proteolysis [GO:0006509],
inflammatory response [GO:0006954],
axon guidance [GO:0007411],
peptidyl-serine phosphorylation [GO:0018105],
platelet activation [GO:0030168],
positive regulation of telomere maintenance via telomerase [GO:0032212],
positive regulation of interleukin-17 production [GO:0032740],
positive regulation of interleukin-4 production [GO:0032753],
intracellular signal transduction [GO:0035556],
Fc-epsilon receptor signaling pathway [GO:0038095],
positive regulation of T cell proliferation [GO:0042102],
positive regulation of interleukin-2 biosynthetic process [GO:0045086],
regulation of megakaryocyte differentiation [GO:0045652],
negative regulation of insulin receptor signaling pathway [GO:0046627],
T cell receptor signaling pathway [GO:0050852],
positive regulation of T cell activation [GO:0050870],
positive regulation of NF-kappaB transcription factor activity [GO:0051092],
positive regulation of telomerase activity [GO:0051973],
cell chemotaxis [GO:0060326],
negative regulation of T cell apoptotic process [GO:0070233],
regulation of platelet aggregation [GO:0090330],
positive regulation of telomere capping [GO:1904355],
positive regulation of T-helper 17 type immune response [GO:2000318],
positive regulation of T-helper 2 cell activation [GO:2000570],
immune system process [GO:0002376],
protein phosphorylation [GO:0006468],
regulation of G2/M transition of mitotic cell cycle [GO:0010389],
phosphorylation [GO:0016310],
positive regulation of protein import into nucleus [GO:0042307],
positive regulation of protein secretion [GO:0050714],
positive regulation of filopodium assembly [GO:0051491],
positive regulation of stress fiber assembly [GO:0051496],

Molecular Function:
protein kinase activity [GO:0004672],
protein serine/threonine kinase activity [GO:0004674],
calcium-dependent protein kinase C activity [GO:0004698],
protein binding [GO:0005515],
ATP binding [GO:0005524],
metal ion binding [GO:0046872],
nucleotide binding [GO:0000166],
protein kinase C activity [GO:0004697],
kinase activity [GO:0016301],
transferase activity [GO:0016740],

Cellular Component:
immunological synapse [GO:0001772],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
aggresome [GO:0016235],
centriolar satellite [GO:0034451],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
membrane [GO:0016020],
neuromuscular junction [GO:0031594],
sarcolemma [GO:0042383],