AUP1
AUP1 lipid droplet regulating VLDL assembly factor
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 28844647 | BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 | Skin, Lung | Human | YES |
GO terms:
Biological Process:
ER-associated ubiquitin-dependent protein catabolic process [GO:0030433],
retrograde protein transport, ER to cytosol [GO:0030970],
regulation of catalytic activity [GO:0050790],
Molecular Function:
protein binding [GO:0005515],
ubiquitin binding [GO:0043130],
ubiquitin-protein transferase activator activity [GO:0097027],
Cellular Component:
Hrd1p ubiquitin ligase ERAD-L complex [GO:0000839],
membrane [GO:0016020],
integral component of endoplasmic reticulum membrane [GO:0030176],
extracellular exosome [GO:0070062],
endoplasmic reticulum [GO:0005783],
integral component of membrane [GO:0016021],