PPA2

inorganic pyrophosphatase 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
tRNA aminoacylation for protein translation [GO:0006418],
protein dephosphorylation [GO:0006470],
phosphate-containing compound metabolic process [GO:0006796],
regulation of mitochondrial membrane potential [GO:0051881],
diphosphate metabolic process [GO:0071344],

Molecular Function:
magnesium ion binding [GO:0000287],
inorganic diphosphatase activity [GO:0004427],
protein serine/threonine phosphatase activity [GO:0004722],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
mitochondrial matrix [GO:0005759],
cytosol [GO:0005829],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],