ATXN2

ataxin 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
negative regulation of receptor internalization [GO:0002091],
regulation of translation [GO:0006417],
regulation of cytoplasmic mRNA processing body assembly [GO:0010603],
RNA metabolic process [GO:0016070],
cytoplasmic mRNA processing body assembly [GO:0033962],
stress granule assembly [GO:0034063],
RNA transport [GO:0050658],
cerebellar Purkinje cell differentiation [GO:0021702],
negative regulation of multicellular organism growth [GO:0040015],
neuron projection morphogenesis [GO:0048812],
homeostasis of number of cells [GO:0048872],
neuromuscular process [GO:0050905],

Molecular Function:
RNA binding [GO:0003723],
epidermal growth factor receptor binding [GO:0005154],
protein binding [GO:0005515],
protein C-terminus binding [GO:0008022],
DBD domain binding [GO:0050692],

Cellular Component:
cytoplasm [GO:0005737],
Golgi apparatus [GO:0005794],
trans-Golgi network [GO:0005802],
cytosol [GO:0005829],
polysome [GO:0005844],
cytoplasmic stress granule [GO:0010494],
membrane [GO:0016020],
perinuclear region of cytoplasm [GO:0048471],
ribonucleoprotein complex [GO:1990904],