ATXN1

ataxin 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
regulation of transcription, DNA-templated [GO:0006355],
RNA processing [GO:0006396],
nervous system development [GO:0007399],
brain development [GO:0007420],
learning [GO:0007612],
memory [GO:0007613],
social behavior [GO:0035176],
negative regulation of transcription, DNA-templated [GO:0045892],
anatomical structure development [GO:0048856],
nuclear export [GO:0051168],
adult locomotory behavior [GO:0008344],
visual learning [GO:0008542],
negative regulation of phosphorylation [GO:0042326],
negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
lung alveolus development [GO:0048286],
excitatory postsynaptic potential [GO:0060079],
positive regulation of glial cell proliferation [GO:0060252],

Molecular Function:
DNA binding [GO:0003677],
protein binding [GO:0005515],
protein C-terminus binding [GO:0008022],
poly(U) RNA binding [GO:0008266],
poly(G) binding [GO:0034046],
identical protein binding [GO:0042802],
protein self-association [GO:0043621],
chromatin binding [GO:0003682],
RNA binding [GO:0003723],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
nucleolus [GO:0005730],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
nuclear matrix [GO:0016363],
nuclear inclusion body [GO:0042405],
macromolecular complex [GO:0032991],