POLG2

DNA polymerase gamma 2, accessory subunit

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
in utero embryonic development [GO:0001701],
DNA-dependent DNA replication [GO:0006261],
mitochondrial DNA replication [GO:0006264],
DNA repair [GO:0006281],
mitochondrion organization [GO:0007005],
respiratory electron transport chain [GO:0022904],
mitochondrial DNA metabolic process [GO:0032042],
mitochondrion morphogenesis [GO:0070584],
DNA biosynthetic process [GO:0071897],
positive regulation of DNA-directed DNA polymerase activity [GO:1900264],
DNA replication [GO:0006260],

Molecular Function:
double-stranded DNA binding [GO:0003690],
DNA-directed DNA polymerase activity [GO:0003887],
protein binding [GO:0005515],
DNA polymerase processivity factor activity [GO:0030337],
identical protein binding [GO:0042802],
DNA polymerase binding [GO:0070182],
DNA binding [GO:0003677],

Cellular Component:
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
mitochondrial matrix [GO:0005759],
gamma DNA polymerase complex [GO:0005760],
mitochondrial nucleoid [GO:0042645],